About Our Lab

We are broadly interested in studying the mechanics of soft engineering and biological materials using an integrated experimental and modeling approach. In particular, we are interested in adaptive materials that  can  exhibit dramatic changes in microstructure, mechanical properties, and  macroscopic shape in response to an environmental stimulus.

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Research

Biomechanics of the Artery

Biomechanics of the Cornea and Sclera

Biomechanics of the Optic Nerve Head

Biomechanics of the Skin

Blast Injury Biomechanics

Collagen Growth and Remodeling

Design of Architected Materials

Dielectric Elastomers

Fracture and Failure Mechanics

Hydrogels

Liquid Crystal Elastomers

Polymers and Composites

Shape Memory Polymers

Recent Publications

L. Zhang, P. Roberts, Z. Wang, J. Liu, S. Schaffter, M. Rubanov, A. Cangialosi, J. Fern, T. D. Nguyen, J. Frechette, R. Schulman “Programming analytic chemomechanical sensing and response in hydrogels with DNA circuits”.

L. Zhang, P. Roberts, Z. Wang, J. Liu, S. Schaffter, M. Rubanov, A. Cangialosi, J. Fern, T. D. Nguyen, J. Frechette, R. Schulman “Programming analytic chemomechanical sensing and response in hydrogels with DNA circuits”, in preparation.

Hydrogels

Z. Yuan, C. A. Czerpak, M. S. Kashaf, H. A. Quigley, T. D. Nguyen, “Biomechanical Strain Responses in the Optic Nerve Head Region in Glaucoma Patients After Intraocular Pressure Lowering

Zhouchen Yuan, C. A. Czerpak, M. S. Kashaf, H. A. Quigley, T. D. Nguyen, “Biomechanical Strain Responses in the Optic Nerve Head Region in Glaucoma Patients After Intraocular Pressure Lowering”, DOI:10.1101/2023.05.30.23290662, in prep.

Optic Nerve Head

S. Aslan, X, Liu, E. Chen, E., M. Mese-Jones, B. Gonzalez, R. O’Hara, Y. Loke, N., Hibino, L. Olivieri, A. Krieger, T. Nguyen, (2024) “Computational Modeling of Arterial Walls: Evaluating Model Complexity and the Influence of Model Parameters on Deformation Outcomes,”, In Proceed- ings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2024) , 1: 454-461, DOI: 10.5220/0012391700003657.

S. Aslan, X, Liu, E. Chen, E., M. Mese-Jones, B. Gonzalez, R. O’Hara, Y. Loke, N., Hibino, L. Olivieri, A. Krieger, T. Nguyen, (2024) “Computational Modeling of Arterial Walls: Evaluating Model Complexity and the Influence of Model Parameters on Deformation Outcomes,”, In Proceed- ings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2024) , 1: 454-461, DOI: 10.5220/0012391700003657. [Link]

C. A. Czerpak, M. S. Kashaf, B. K. Zimmerman, Rebecca Mirville. Nicolas Gasquet, H. A. Quigley, T. D. Nguyen, “The Strain Response to Intraocular Pressure Increase in the Lamina Cribrosa of Control Subjects and Glaucoma Patients”, Translational Vision Science and Technology, accepted in October 2024.

C. A. Czerpak, M. S. Kashaf, B. K. Zimmerman, Rebecca Mirville. Nicolas Gasquet, H. A. Quigley, T. D. Nguyen, “The Strain Response to Intraocular Pressure Increase in the Lamina Cribrosa of Control Subjects and Glaucoma Patients”, Translational Vision Science and Technology, accepted in October 2024.

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